Ensure quality mixtures and reduce processing times with the Alfa Laval Hybrid Powder Mixer. Unmatched reliability and mixing efficiency make it suitable for powder induction, mixing and dissolution in industries that place high demands on hygiene and ease of cleaning, including food, dairy, beverage, pharmaceutical, and industrial manufacturing. Interactive mixtures for example can be used in the manufacturing of tablets [11] enhancing the dissolution of poorly soluble drugs [12] or for nasal administration. [3] One common application is for inhalation therapy, where the concept has been used in the development of alternatives to pressurised metered dose inhalers. [13] We supply a wide range of powder processing equipment suitable for any scale, from R&D through to commercial production. A British, 100-year-old company manufactures and supplies the global baking market with high quality produce. They supply a wide range of customer types from individual craft bakers to high street and supermarket chains. The quality by design initiative (QbD) of the U.S. Food and Drug Administration requires a process to be controllable and predictable. Theories and methods to characterize powder mixture have facilitated the implementation of QbD approaches to predict flow properties of powder mixture. For example, QbD approach is shown to be useful for predicting flow performance and finding design space during formulation development. [14]

Furthermore, powder mixing equipment is itself endlessly diverse. Industrial mixing systems come in all shapes and sizes and perform any number of different powder blending techniques and mixing processes. Tablet coating – Powdery active ingredients can be coated to accelerate or inhibit solubility or oxidization. Continuous or batch production – Does your production process operate continuously or in batches? The advantages and disadvantages of continuous mixers vs. batch mixers depends on your product, facilities, and desired output.J. Bridgewater (1976). "Fundamental powder mixing mechanisms". Powder Technol. 15 (2): 215–236. doi: 10.1016/0032-5910(76)80051-4. Cleaning and hygiene – Is cross contamination a concern for your product? Will the powder mixer need to be cleaned between batches? amixon ® powder mixers are built with food-grade materials like stainless steel and grant full access to the mixing chamber and agitator shaft, making for especially easy CIP and fast drying. Our engineers design and project-manage major industrial installations in many sectors including chemical, mining, additive manufacturing, aerospace, food and pharmaceutical, and deliver equipment which achieves product consistency and homogeneity. As your business and output grow, it’s natural to consider investing in equipment that better suits demand. Here at Winkworth we provide every opportunity to evaluate your mixer needs prior to making an investment. Get In Touch

Whether you require a single unit of equipment for installation into an existing system or the design, manufacture, installation and commissioning of a complete large-scale turnkey system, we can help. MIXACO powder mixers are available in all sizes: Laboratory mixers for powders for small batches and product development from 5 liters up to mixers for 10,000 liter batches. MIXACO powder mixers mix and process all types of powders – in small batches from 5 liters and up to capacities of 10,000 liters. Powder mixing equipment plays a crucial role across many industries that involve bulk solids processing. From pharmaceuticals to chemical processing to the food industry, there are countless applications for high-performance powder mixing.

Welcome to our Knowledge Centre, your resource for valuable insight and support. Whether you’re seeking answers to frequently asked questions or looking for additional resources to assist you in selecting the perfect mixing solutions, you’ve come to the right place. Our Knowledge Centre is continuously updated to reflect the latest advancements in mixing technology and industry trends. Get In Touch P. Kulvanich & P.J. Stewart (1987). "The effect of particle size and concentration on the adhesive characteristics of a model drug-carrier interactive system". J Pharm Pharmacol. 39 (9): 673–678. doi: 10.1111/j.2042-7158.1987.tb06968.x. PMID 2890731. S2CID 6880102. Batch sizes – The volume of powders to be mixed can affect loading and discharge times, mixing techniques, change overs, and mixing time among other things. Our high-efficiency powder mixers can be constructed at a wide range of proportions for varying batch sizes and filling levels. From a small dry powder mixer to a thousand-liter tank, amixon ® can engineer precisely the powder blending machine you need.

Generally, space in a factory comes at a premium, there is never enough space and you certainly don’t want to waste it. If you need to buy multiple industrial mixers to cover the range of batch sizes you produce, then these will all take up valuable room on the factory floor. Depending on the product you are producing, the industrial mixer may need to be housed in a 'clean room', which is expensive to construct and maintain. If you have multiple mixers then the costs of these 'clean rooms' spiral.

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THE BLENDING CHALLENGE Industrial Powder Mixing Arguably one of the most important stages in a powder processing system is that of Blending. Blend uniformity – Powder blends consisting of highly-concentrated active ingredients and excipients such as starch and cellulose are gently and thoroughly homogenized. Evenly blending exact amounts of powdered active ingredient with excipients is not without its difficulties. Achieving and documenting batch uniformity is among the most significant ongoing challenges facing the pharmaceutical industry.