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In the ITT population ( n = 329), the median [range] time to recovery was significantly shorter in the diosmectite group (53.8 hours [3.7–167.3]) than in the placebo group (69.0 hours [2.0–165.2]) when tested with Wilcoxon's test ( P = .0294). The difference between the two groups was 15.2 hours. The statistical significance of this effect was also evidenced by the post hoc analysis using the time-to-event Gehan-Wilcoxon test considering censored data: 56.3 hours [47.7– 68.0] in the diosmectite group versus 72.2 [63.3– 82.0] hours in the placebo group ( P = .0291). The contents of the sachet can be added and thoroughly stirred in the feeding bottle with 50ml of water, to be given at intervals during the day, or thoroughly mixed with a semi-liquid food: broth, stewed fruit, mashed vegetables or baby food. Diosmectite, an activated natural aluminosilicate clay consisting of a double aluminium and magnesium silicate, is an adsorbent widely used for the treatment of acute infectious diarrhoea in children. In children, diosmectite efficacy in the treatment of acute watery diarrhoea has been assessed in a recent meta-analysis. Combined data from six randomized, controlled trials have shown that diosmectite significantly reduces diarrhoea duration by one day and increases the chance of recovery on intervention day three versus control group [ 9]. Two recent trials have indicated that diosmectite reduces stool output (versus placebo) in children with acute watery diarrhoea [ 10]. Smecta drug does not have any indication for pregnant and lactating women. Therefore, before using, you should consult your doctor to weigh the benefits and risks of the drug. Above has summarized all information about the drug Smecta that you can refer. To get the best results when using, you first need to learn more about the drug along with the instructions and instructions of a specialist to ensure it is safe to use.
Children and adults have acute – chronic diarrhea due to a number of causes such as food poisoning, infection, and inadequate diet.Also, not everyone knows how to drink Smecta, in what dosage. Instructions for use Smecta provides an answer to this question. The usual dosage for adults and adolescents is 3 sachets per day. It is necessary to observe the interval between taking the drug and eating about 1-2 hours. Symptomatic treatment of acute diarrhoea in children and infants in addition to oral rehydration and in adults; Store the product in a dry, cool place, avoid moisture and should be kept at temperatures below 25 degrees C. Despite significantly shorter time to recovery in the diosmectite group, the proportions of patients achieving recovery were similar in both groups at the end of the study. This is explained by acute watery diarrhoea being self-resolving within seven days.
Smecta ® is available without a doctor’s prescription to assist in the management of acute and chronic diarrhoea. Nevertheless, you still need to use Smecta® carefully to get the best results from it. SmectaGo ® is a ready to drink liquid preparation to be taken orally. The content of the sachet can be swallowed directly. Treatment for acute diarrhoea Diosmectite may be a useful additive in the treatment of acute childhood diarrhoea. As evidence is of ‘low quality’, future research is needed with higher quality designs before any firm recommendations can be made. [2] See also [ edit ] Smecta drugs can be prescription or over-the-counter without a prescription. The drug is indicated in the following cases:a b Lee KJ (October 2015). "Pharmacologic Agents for Chronic Diarrhea". Intestinal Research. 13 (4): 306–312. doi: 10.5217/ir.2015.13.4.306. PMC 4641856. PMID 26576135. Diosmectite (brand names Smecta, Smecdral) is a natural silicate of aluminium and magnesium used as an intestinal adsorbent in the treatment of several gastrointestinal diseases, including infectious and non-infectious acute and chronic diarrhoea, including irritable bowel syndrome diarrhea subtype. Other uses include: chronic diarrhea caused by radiation-induced, chemotherapy-induced, and HIV/AIDS-associated chronic diarrhea. [1]
If you have fructose intolerance (rare hereditary illness), due to the presence of glucose and saccharose. Medication that protects the digestive tract by lining the mucosa with a protective film and decreasing the acidity of the stomach. This type of medication may interfere with the absorption of other drugs.Diosmectite ................................................. .................................................. ................ 3,000 g What is SMECTA 3 g ORANGE-VANILLA, powder for oral suspension in sachets and in which cases it is used?
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